Report title:forGenome-wide epigenetic modificationFeature identification and application
Report time:9month25Sunday afternoon16.45-17.45
Reporting location:Computer Best Online Casino Games 2024 South University313Conference Room
Reporter:Zhang Yan Professor
ReportAbstract：
With the development of genome sequencing Best Online Casino Games 2024，For the epigenome in physiology、The study of dynamic changes in pathological processes and even the analysis of the microevolutionary process of the epigenome brings hope。Characteristic in the human genomeDNAMethylation marks and histone modifications,RNAThe continuous discovery and precise analysis of modifications help to gradually improve the understanding of epigenetic regulation mechanisms，To gain a deeper understanding of cell lines/The mechanisms of tissue phenotypes and disease phenotypes。This Best Online Casino Games 2024 group focuses on differentDNAData from methylation detection Best Online Casino Games 2024 developed for differential useDNAMethylation screening tools and gene methylation function analysis tools。For the whole genomeDNAMethylation, histone modification,RNADeveloped a series of analysis methods for modification and other data，Discover disease-related biological characteristics。In addition，Integrating the clinical information and epigenetic characteristics Best Online Casino Games 2024 disease by building a machine learning prediction model can be used to screen key factors for disease diagnosis and prognostic assessment。So we can mine epigenetic characteristics related to different phenotypes from massive data，Can be promotedDNAApplication and transformation of biomarkers such as methylation.
About the speaker：
Zhang Yan，Professor, School of Life Science and Best Online Casino Games 2024, Harbin Institute of Best Online Casino Games 2024，Director of Computational Biology Research Center。Director of the Functional Genomics and Systems Biology Branch of the Chinese Society of Cell Biology，Chairman of the Tumor Sequencing and Big Data Analysis Expert Committee of the Tumor Markers Committee of the Chinese Anti-Cancer Association，Member of the Bioinformatics Committee of the China Computer Federation。Member of the Digital Medicine and Medical Informatization Branch of the Chinese Society of Biomedical Engineering。Studying at Niigata University in Japan for master's and doctoral degrees，2006After studying abroad and returning to China, he has been engaged in teaching and scientific research in the field of bioinformatics。The research direction involves clinical medical data、Tumor Biology、Data analysis and Best Online Casino Games 2024 platform development in developmental biology and other fields。A series of research results published in "Nucleic Acids Best Online Casino Games 2024》,《Molecular Oncology》,《Development》,《Epigenomics》,《Briefings in Bioinformatics》,《Database" and other magazines.
